Ninein-KO in mice: potential role in dwarfism and microcephaly?

Event Details

  • Date:
  • Venue: IRB Barcelona - Auditorium
  • Address: Parc Científic de Barcelona C/ Baldiri Reixac 10, 08028 Barcelona
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IRB Barcelona BioMed Seminar

by Andreas Merdes, PhD. – Group Leader – Biology of the Centrosome – Paul Sabatier – University Toulouse III – Centre de Biologie Intégrative – Toulouse, France.



We observed growth defects in ninein knockout mice that were reminiscent of human primordial dwarfism. Further analysis revealed developmental abnormalities in bone tissue. I will discuss potential cellular mechanisms that lead to the observed defects.


Host: Jens Lüders, PhD., – Group Leader – IRB Barcelona – Mechanisms of Disease Programme.