IRB Seminar: Stem Cells in Silence, Action and Cancer


Event Details

  • Date:

Speaker: Elaine Fuchs, PhD. Howard Hughes Medical Institute, The Rockefeller University. New York (USA)

Host: Dr. Edurard Batlle, IRB Barcelona

Abstract

Adult tissue stem cells have the ability to self-renew long term and differentiate into one or more tissues. Many stem cells are used sparingly to replenish cells during normal homeostasis. However, even stem cells that are quiescent must be able to respond quickly to injury in order to fuel rapid tissue regeneration. How stem cells balance self-renewal and differentiation is of fundamental importance to our understanding of normal tissue maintenance and wound repair. Increasing evidence suggests that the regulatory circuitry governing this balancing act is at the root of some types of cancers.

More information at IRB Barcelona website.